Dana L. Smith
Dana Smith graduated from UNCG and received an MA from the UC-Berkeley Department of Microbiology and Immunology. At UCSF she managed the laboratories of Dr. Alexander Johnson (1986-1991) and Dr Andrew Murray (1991-2000),while pursuing respective research projects on transcription regulation and cell biology.
She joined Dr. Elizabeth Blackburn’s lab as lab manager and researcher in 2000 and for many years studied the role of telomere biology in the regulation of yeast mitosis and meiosis. Since2016, she has worked with Dr. Jue Lin, as part of the Telomere Core, working on a variety of studies aimed at understanding the role of telomere maintenance in human health and disease.
She has worked on many of the Blackburn Telomere Core study contributions to the Telomere Research Network and has collaborated with many scientists in developing new telomere-length assays in non-human animal species, including cats, macaques, and lemurs.
For many years she has been a leader in the UCSF Laboratory Resource Group, an organization of lab managers and campus representatives, devoted to facilitating communication around topics impactful to researchers.
Telomere length is associated with disability progression in multiple sclerosis.
Annals of neurology
Krysko KM, Henry RG, Cree BAC, Lin J
Telomere length measurement by qPCR - Summary of critical factors and recommendations for assay design.
Lin J, Smith DL, Esteves K, Drury S
Early telomerase inactivation accelerates aging independently of telomere length.
Xie Z, Jay KA, Smith DL, Zhang Y, Liu Z, Zheng J, Tian R, Li H, Blackburn EH
Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.
Genes & development
Anderson CM, Korkin D, Smith DL, Makovets S, Seidel JJ, Sali A, Blackburn EH
Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response.
Molecular biology of the cell
Lin J, Smith DL, Blackburn EH