Selected Core Publications
Lin J, Epel E. Stress and telomere shortening: Insights from cellular mechanisms. Ageing Res Rev. 2022 Jan;73:101507. doi: 10.1016/j.arr.2021.101507. Epub 2021 Nov 1. Review. PubMed PMID: 34736994; PubMed Central PMCID: PMC8920518.
Protsenko E, Rehkopf D, Prather AA, Epel E, Lin J. Are long telomeres better than short? Relative contributions of genetically predicted telomere length to neoplastic and non-neoplastic disease risk and population health burden. PLoS One. 2020;15(10):e0240185. doi: 10.1371/journal.pone.0240185. eCollection 2020. PubMed PMID: 33031470; PubMed Central PMCID: PMC7544094.
Lin J, Smith DL, Esteves K, Drury S. Telomere length measurement by qPCR - Summary of critical factors and recommendations for assay design. Psychoneuroendocrinology. 2019 Jan;99:271-278. doi: 10.1016/j.psyneuen.2018.10.005. Epub 2018 Oct 10. Review. PubMed PMID: 30343983; PubMed Central PMCID: PMC6363640.
Lin J, Sun J, Wang S, Milush JM, Baker CAR, Coccia M, Effros RB, Puterman E, Blackburn E, Prather AA, Epel E. In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study. Psychoneuroendocrinology. 2018 Oct;96:179-187. doi: 10.1016/j.psyneuen.2018.06.020. Epub 2018 Jun 26. PubMed PMID: 29980010.
Stout SA, Lin J, Hernandez N, Davis EP, Blackburn E, Carroll JE, Glynn LM. Validation of Minimally-Invasive Sample Collection Methods for Measurement of Telomere Length. Front Aging Neurosci. 2017;9:397. doi: 10.3389/fnagi.2017.00397. eCollection 2017. PubMed PMID: 29270121; PubMed Central PMCID: PMC5723637.
Auld E, Lin J, Chang E, Byanyima P, Ayakaka I, Musisi E, Worodria W, Davis JL, Segal M, Blackburn E, Huang L. HIV Infection Is Associated with Shortened Telomere Length in Ugandans with Suspected Tuberculosis. PLoS One. 2016;11(9):e0163153. doi: 10.1371/journal.pone.0163153. eCollection 2016. PubMed PMID: 27655116; PubMed Central PMCID: PMC5031464.
Blackburn EH, Epel ES, Lin J. Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection. Science. 2015 Dec 4;350(6265):1193-8. doi: 10.1126/science.aab3389. Review. PubMed PMID: 26785477.
Lapham K, Kvale MN, Lin J, Connell S, Croen LA, Dispensa BP, Fang L, Hesselson S, Hoffmann TJ, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Matsuguchi T, McGuire WB, Miles S, Quesenberry CP Jr, Rowell S, Sadler M, Sakoda LC, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Kwok PY, Risch N, Schaefer C, Blackburn EH. Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug;200(4):1061-72. doi: 10.1534/genetics.115.178624. Epub 2015 Jun 19. PubMed PMID: 26092717; PubMed Central PMCID: PMC4574243.
Needham BL, Rehkopf D, Adler N, Gregorich S, Lin J, Blackburn EH, Epel ES. Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002. Epidemiology. 2015 Jul;26(4):528-35. doi: 10.1097/EDE.0000000000000299. PubMed PMID: 26039272; PubMed Central PMCID: PMC4679150.
Zalli A, Carvalho LA, Lin J, Hamer M, Erusalimsky JD, Blackburn EH, Steptoe A. Shorter telomeres with high telomerase activity are associated with raised allostatic load and impoverished psychosocial resources. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4519-24. doi: 10.1073/pnas.1322145111. Epub 2014 Mar 10. PubMed PMID: 24616496; PubMed Central PMCID: PMC3970484.
Ornish D, Lin J, Chan JM, Epel E, Kemp C, Weidner G, Marlin R, Frenda SJ, Magbanua MJM, Daubenmier J, Estay I, Hills NK, Chainani-Wu N, Carroll PR, Blackburn EH. Effect of comprehensive lifestyle changes on telomerase activity and telomere length in men with biopsy-proven low-risk prostate cancer: 5-year follow-up of a descriptive pilot study. Lancet Oncol. 2013 Oct;14(11):1112-1120. doi: 10.1016/S1470-2045(13)70366-8. Epub 2013 Sep 17. PubMed PMID: 24051140; NIHMSID:NIHMS540047.
Aviv A, Hunt SC, Lin J, Cao X, Kimura M, Blackburn E. Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR. Nucleic Acids Res. 2011 Nov 1;39(20):e134. doi: 10.1093/nar/gkr634. Epub 2011 Aug 8. PubMed PMID: 21824912; PubMed Central PMCID: PMC3203599.
Entringer S, Epel ES, Kumsta R, Lin J, Hellhammer DH, Blackburn EH, Wüst S, Wadhwa PD. Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):E513-8. doi: 10.1073/pnas.1107759108. Epub 2011 Aug 3. PubMed PMID: 21813766; PubMed Central PMCID: PMC3158153.
Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S, Blackburn E. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. J Immunol Methods. 2010 Jan 31;352(1-2):71-80. doi: 10.1016/j.jim.2009.09.012. Epub 2009 Oct 21. PubMed PMID: 19837074; PubMed Central PMCID: PMC3280689.
Farzaneh-Far R, Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA. Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA. 2010 Jan 20;303(3):250-7. doi: 10.1001/jama.2009.2008. PubMed PMID: 20085953; PubMed Central PMCID: PMC2819264.
Ornish D, Lin J, Daubenmier J, Weidner G, Epel E, Kemp C, Magbanua MJ, Marlin R, Yglecias L, Carroll PR, Blackburn EH. Increased telomerase activity and comprehensive lifestyle changes: a pilot study. Lancet Oncol. 2008 Nov;9(11):1048-57. doi: 10.1016/S1470-2045(08)70234-1. Epub 2008 Sep 15. PubMed PMID: 18799354.
Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD, Cawthon RM. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17312-5. doi: 10.1073/pnas.0407162101. Epub 2004 Dec 1. PubMed PMID: 15574496; PubMed Central PMCID: PMC534658.